2008 ~ 2017

2017

Oncotarget 

2017 Dec 13;9(1):1143-1155 

Kim W, Pyo J, Noh BJ, Jeong JW, Lee J, Kim JE*

CCAR2 negatively regulates IL-8 production in cervical cancer cells 

2017

Br J Pharmacol 

2017 Jun;174(12):1810-1825. 

Choi M(co-first), Min YH(co-first), Pyo J, Lee CW, Jang CY, Kim JE*

TC Mps1 12, a novel Mps1 inhibitor, suppresses a growth of hepatocellular carcinoma cells via accumulated chromosomal instability. 

2017

Biochem Biophys Res Commun 

2017 Apr 15;485(4):782-789.

Kim W, Cheon MG, Kim JE*

Mitochondrial CCAR2/DBC1 is required for cell survival against rotenone-induced mitochondrial stress 

2016

Oncotarget 

2016 Dec 20; 7(51): 84718-84735.

Min YH, Kim W, Kim JE*

The Aurora kinase A inhibitor TC-A2317 disrupts mitotic progression and inhibits cancer cell proliferation 

2016

Oncotarget 

2016 Jun 14; 7(30): 47253-47241. 

Bae WY, Choi JS, Kim JE, Park C, Jeong JW. 

Zingerone suppresses angiogenesis via inhibition of matrix metalloproteinases during tumor development

2016

Cancer Lett 

2016 Apr 1;373(1):138-145. 

Lee SD, Kim W, Jeong JW, Park JW, Kim JE*

AK-1, a SIRT2 inhibitor, destabilizes HIF-1α and diminishes its transcriptional activity during hypoxia

2016

Oncotarget 

2016 Mar 14; 7(17):23975-23987. 

Shin DH, Choi YJ, Jin P, Yoon H, Chun YS, Shin HW, Kim JE, Park JW. 

Distinct effects of SIRT1 in cancer and stromal cells on tumor promotion 

2015

Biochem Pharmacol 

2015 Nov 1; 98(1):41-50. 

Bae WY, Choi JS, Kim JE, Jeong JW. 

Cinnamic aldehyde suppresses hypoxia-induced angiogenesis via inhibition of hypoxia-inducible factor-1α expression during tumor progression

2015

Cancer Lett 

2015 Feb 28;357(2):591-601.

Choi M, Kim W, Cheon MG, Lee CW, Kim JE*

Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells

2015

Cancer Lett 

2015 Jan 28;356(2 Pt B):637-645.

Cheon MG, Kim W, Choi M, Kim JE*

AK-1, a specific SIRT2 inhibitor, induces cell cycle arrest by downregulating Snail in HCT116 human colon carcinoma cells

2014

Nucleic Acids Res 

2014 Dec 1;42(21):13150-13160.

Magni M, Ruscica V, Buscemi G, Kim JE, Nachimuthu BT, Fontanella E, Delia D, Zannini L. 

Chk2 and REGγ-dependent DBC1 regulation in DNA damage induced apoptosis 

2014

Tumor Biol 

2014 Nov; 35(11):10919-10929.

Kim W, Jeong JW, Kim JE*

CCAR2 deficiency augments genotoxic stress-induced apoptosis in the presence of melatonin in non-small cell lung cancer cells  

2014

Phytother Res 

2014 Aug; 28(8):1246-1251.

Kong CS, Kim KH, Choi JS, Kim JE, Park C, Jeong JW. 

Salicin, an Extract from White Willow Bark, Inhibits Angiogenesis by Blocking the ROS-ERK Pathways. 

2014

Cell Cycle 

2014 Mar; 13(5): 726-738.

Kim W, Choi M, Kim JE*. 

The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle

[Review]

2013

J Physiol Pharmacol 

2013 Oct; 64(5):531-534. 

Kim W, Kim JE*. 

SIRT7 an emerging sirtuin: Deciphering newer roles. 

[Review]

2013

Cancer Lett 

2013 Jun 10; 333(2):180-186.

Kim W, Kim JE*. 

Deleted in breast cancer 1 (DBC1) deficiency results in apoptosis of breast cancer cells through impaired responses to UV-induced DNA damage.

2012

J Mol Cell Biol 

2012 Oct; 4(5):294-303. 

Zannini L, Buscemi G, Kim JE, Fontanelia E, Delia D. 

DBC1 phosphorylation by ATM/ATR inhibits SIRT1 deacetylase in response to DNA damage. 

2012

J Biol Chem 

2012 Feb 17; 287(8):5588-5599. 

Kim W, Kim R, Park G, Park JW*, Kim JE*

The deficiency of H3K79 histone methyltransferase DOT1L inhibits cell proliferation

2011

FEBS Lett 

2011 Jan 3; 585(1):219-224.

Park G, Jeong JW, Kim JE*

SIRT1 deficiency attenuates MPP+-induced apoptosis in dopaminergic cells

2010

Mol Cell 

2010 Jun 25; 38(6):864-878.

Lim JH, Lee YM, Chun YS, Chen J, Kim JE* (co-corresponding), Park JW*. 

Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha 

2010

Cancer Sci 

2010 Jul; 101(7):1738-1744.

Sung JY, Kim R*(co-first), Kim JE* (co-corresponding), Lee J*.

The balance between SIRT1 and DBC1 expression is lost in breast cancer 

2010

Protein J 

2010 Apr; 29(3):213-223. 

Park G, Gong Z, Chen J, Kim JE*

Characterization of the DOT1L network: Implications of diverse roles for DOT1L 

2010

Neoplasma 

2010;57(4):365-368. 

Kim JE*, Sung S. 

Deleted in Breast Cancer 1 (DBC1) is a dynamically regulated protein 

2010

Mol Cell 

2010 Feb 12; 37(3):438-446.

Gong Z, Kim JE, Leung CC, Glover JN, Chen J. 

BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control 

2009

Cell Cycle 

2009 Nov 15; 8(22):3784-3785.

Kim JE*, Lou Z, Chen J. 

Interactions between DBC1 and SIRT1 are deregulated in breast cancer cells 

2009

Cell Cycle 

2009 Sep 15; 8(18):2932-2935. 

Kim JE* (co-corresponding), Chen J, Lou Z*. 

p30 DBC is a potential regulator of tumorigenesis 

[Review]

2009

J Biol Chem 

2009 Mar 13; 84(11):7284-7293.

Gong Z, Cho YW, Kim JE, Ge K, Chen J. 

Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage 

2008

Mol Cell Biol 

2008 Apr; 28(8):2825-2839. 

Steger DJ, Lefterova MI, Ying L, Stonestrom AJ, Schupp M, Zhou D, Vakoc AL, Kim JE, Chen J, Lazar MA, Blobel GA, Vakoc CR 

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. 

2008

Nature 

2008 Jan 31; 451(7178):583-586.

Kim JE, Chen J, Lou Z. 

DBC1 is a negative regulator of SIRT1